Fast myelin water fraction estimation using 2D multislice CPMG
نویسندگان
چکیده
منابع مشابه
Improved estimation of myelin water fraction using complex model fitting
In gradient echo (GRE) imaging, three compartment water modeling (myelin water, axonal water and extracellular water) in white matter has been demonstrated to show different frequency shifts that depend on the relative orientation of fibers and the B0 field. This finding suggests that in GRE-based myelin water imaging, a signal model may need to incorporate frequency offset terms and become a c...
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PURPOSE To assess neuroprotection and remyelination in Multiple Sclerosis (MS), we applied a more robust myelin water imaging (MWI) processing technique, including spatial priors into image reconstruction, which allows for lower SNR, less averages and shorter acquisition times. We sought to evaluate this technique in MS-patients and healthy controls (HC). MATERIALS AND METHODS Seventeen MS-pa...
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PURPOSE Myelin content is a marker for nervous system pathology and is quantifiable by myelin water imaging using multi-echo CPMG sequence, which is inherently slow. One way to accelerate the scan is to utilize compressed sensing. However, reconstructing the images piecemeal by standard compressed sensing methods is not the optimal solution, because it only exploits intraimage spatial redundanc...
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ژورنال
عنوان ژورنال: Magnetic Resonance in Medicine
سال: 2015
ISSN: 0740-3194
DOI: 10.1002/mrm.26034